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            D-フェニルアラニン

            D-フェニルアラニン 化學構造式
            673-06-3
            CAS番號.
            673-06-3
            化學名:
            D-フェニルアラニン
            別名:
            D-フェニルアラニン;(R)-3-フェニル-2-アミノプロピオン酸;(R)-α-アミノベンゼンプロパン酸;(R)-2-ベンジルグリシン;(R)-2-アミノ-3-フェニルプロピオン酸;(+)-D-フェニルアラニン;(2R)-2-アミノ-3-フェニルプロピオン酸;(+)-フェニルアラニン;(R)-2-アミノ-3-フェニルプロパン酸;D-フェニルアラニン (R)-(+)-;D‐フェニルアラニン;D(+)-フェニルアラニン
            英語化學名:
            D-Phenylalanine
            英語別名:
            PHENYLALANINE;d-phe;H-D-PHE-OH;D-Phe-OH;(R)-PHENYLALANINE;(R)-2-amino-3-phenylpropanoic acid;NSC 25005;nci-c60195;Endorphenyl;D-Phenylalanin
            CBNumber:
            CB9773699
            化學式:
            C9H11NO2
            分子量:
            165.19
            MOL File:
            673-06-3.mol

            D-フェニルアラニン 物理性質

            融點 :
            273-276 °C(lit.)
            沸點 :
            293.03°C (rough estimate)
            比旋光度 :
            33.5 º (c=2, H2O)
            比重(密度) :
            1.1603 (rough estimate)
            屈折率 :
            34 ° (C=2, H2O)
            貯蔵溫度 :
            Store at RT.
            溶解性:
            Methanol (Slightly), Water (Slightly)
            外見 :
            Powder
            酸解離定數(Pka):
            2.2(at 25℃)
            色:
            White to off-white
            水溶解度 :
            27 g/L (20 ºC)
            Merck :
            14,7271
            BRN :
            2804068
            安定性::
            Stable. Incompatible with strong oxidizing agents, acids, bases.
            InChIKey:
            COLNVLDHVKWLRT-MRVPVSSYSA-N
            CAS データベース:
            673-06-3(CAS DataBase Reference)
            EPAの化學物質情報:
            D-Phenylalanine (673-06-3)

            安全性情報

            主な危険性  Xi,C
            Rフレーズ  34
            Sフレーズ  24/25-45-36/37/39-27-26
            WGK Germany  3
            RTECS 番號 AY7533000
            Hazard Note  Irritant
            TSCA  Yes
            HSコード  29224995
            毒性 TDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82
            化審法 (9)-1282 屆出不要化學物質

            D-フェニルアラニン 価格 もっと(34)

            メーカー 製品番號 製品説明 CAS番號 包裝 価格 更新時間 購入
            富士フイルム和光純薬株式會社(wako) W01COBST-8046 D-フェニルアラニン
            D-Phenylalanine
            673-06-3 5g ¥3600 2021-03-23 購入
            富士フイルム和光純薬株式會社(wako) W01COBST-8046 D-フェニルアラニン
            D-Phenylalanine
            673-06-3 25g ¥5400 2021-03-23 購入
            東京化成工業 P0135 D-フェニルアラニン >98.0%(T)
            D-Phenylalanine >98.0%(T)
            673-06-3 5g ¥2500 2022-04-26 購入
            東京化成工業 P0135 D-フェニルアラニン >98.0%(T)
            D-Phenylalanine >98.0%(T)
            673-06-3 25g ¥7300 2022-04-26 購入
            関東化學株式會社(KANTO) 32098-60 D‐フェニルアラニン >98.0%(T)
            D‐Phenylalanine >98.0%(T)
            673-06-3 1g ¥4800 2021-03-23 購入

            D-フェニルアラニン MSDS


            D-alpha-Amino-beta-phenylpropionic acid

            D-フェニルアラニン 化學特性,用途語,生産方法

            外観

            白色~わずかにうすい褐色, 結晶性粉末~粉末

            溶解性

            水にやや溶けにくく、エタノール及びジエチルエ-テルにほとんど溶けない。

            用途

            アミノ酸研究、ペプチド原料あるいは醫?農薬の不斉骨格源。

            説明

            D-Phenylalanine, also known as D-alpha-Amino-beta-phenylpropionic acid, is a kind of non-proteinogenic amino acid. The biological function of D-phenylalanine remains unclear. However, it has certain anti-depressant, analgesic activities and pharmacological activity at niacin receptor II. The mechanism action of its analgesic activity seems to originate from its inhibition of enkephalin degradation by the carboxypeptidase A. Enkephalins are part of your body’s natural pain relief system. When they are broken down by enkephalinase, this contributes to the sensation of pain. D-Phenylalanine is specifically thought to be beneficial for reducing feelings of chronic pain. D-phenylalanine has been used with mixed results to treat chronic pain, including pain caused by rheumatoid arthritis. The primary use of D-phenylalanine as a health supplement is the relief of discomfort.

            化學的特性

            White crystalline powder

            使用

            D-Phenylalanine, the stereoisomer of L-Phenylalanine (P319415) has been used in the synthesis of Schaeffer’s acid analogues as important structures in tuberculostatic design. They exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.

            定義

            ChEBI: D-phenylalanine is the D-enantiomer of phenylalanine. It is a phenylalanine and a D-alpha-amino acid. It is a conjugate base of a D-phenylalaninium. It is a conjugate acid of a D-phenylalaninate. It is an enantiomer of a L-phenylalanine. It is a tautomer of a D-phenylalanine zwitterion.

            一般的な説明

            D-phenylalanine appears as needles or prisms.

            空気と水の反応

            Water soluble. Aqueous solutions are weakly acidic.

            反応プロフィール

            D-alpha-Amino-beta-phenylpropionic acid may be light sensitive. D-alpha-Amino-beta-phenylpropionic acid reacts with strong oxidizing agents, acids and bases. . Act as weak acids in solution.

            火災危険

            Flash point data for D-alpha-Amino-beta-phenylpropionic acid are not available, however D-alpha-Amino-beta-phenylpropionic acid is probably combustible.

            安全性プロファイル

            Mildly toxic by intraperitoneal route. Human systemic effects by ingestion: nausea, hypermotility, diarrhea. When heated to decomposition it emits toxic fumes of NOx.

            參考文獻

            https://www.alfa.com/en/catalog/A10572/
            https://en.wikipedia.org/wiki/Phenylalanine
            Christianson, D. W., et al. "Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A. " Journal of Biological Chemistry264.22(1989):12849-53.

            D-フェニルアラニン 上流と下流の製品情報

            原材料

            準備製品


            D-フェニルアラニン 生産企業

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            673-06-3(D-フェニルアラニン)キーワード:


            • 673-06-3
            • D-PHENYLALANINE, >=98% (HPLC)
            • D-beta-Phenyl-alpha-aminopropionic acid
            • d-alpha-aminohydrocinnamic acid
            • D-ALPHA-AMINO-BETA-PHENYL-PROPIONIC ACID
            • D-2-AMINO-3-PHENYLPROPANOIC ACID
            • D(+)-PHENYLALANINE
            • D-PHENYLALANINE
            • RARECHEM AB PP 0687
            • (R)-2-AMINO-3-PHENYLPROPIONIC ACID
            • D-PHENYLALANINE, 99+% (98% EE/GLC)
            • D-Phenylalanine,>99%
            • D-α-Amino-β-phenylpropionic acid
            • Alanine, phenyl-, D- (8CI)
            • D-a-Amino-b-phenylpropionic acid
            • D-b-Phenylalanine
            • D-Phenylalanine (9CI)
            • NSC 25005
            • D-Phenylalanin
            • D-Phenglalanine,(R)-(+)-Phenglalanine
            • H-D-PHE-OH D-PHENYLALANINE
            • D-PHENYLALANINE ((R)-PHENYLALANINE)
            • (2R)-2-Amino-3-phenylpropanoic acid
            • (2R)-2-Amino-3-phenylpropionic acid
            • (R)-2-Benzylglycine
            • D-Phenylalanine≥ 99% (Assay)
            • D-PHENYLALANINE extrapure CHR
            • (R)-(+)-Phenylalanine, (R)-2-Amino-3-phenylpropionic acid, D-2-Amino-3-phenylpropanoic acid
            • nci-c60195
            • D-Phenylalanine,(R)-2-Amino-3-phenylpropionic acid
            • D-Phenylalanine Vetec(TM) reagent grade, >=98%
            • D-フェニルアラニン
            • (R)-3-フェニル-2-アミノプロピオン酸
            • (R)-α-アミノベンゼンプロパン酸
            • (R)-2-ベンジルグリシン
            • (R)-2-アミノ-3-フェニルプロピオン酸
            • (+)-D-フェニルアラニン
            • (2R)-2-アミノ-3-フェニルプロピオン酸
            • (+)-フェニルアラニン
            • (R)-2-アミノ-3-フェニルプロパン酸
            • D-フェニルアラニン (R)-(+)-
            • D‐フェニルアラニン
            • D(+)-フェニルアラニン
            • α-アミノ酸
            • アミノ酸
            • 生化學
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